Catalog No: CY5992 Reactivity: Human Mouse Rat
Isotype: Rabbit IgG Applications: WB ICC/IF IP
UniProt ID: Q9GZQ8
All Names: ATG8F; LC3B; MAP1LC3B; MLP3B; MAP1LC3B;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 14,16 kDa
WB 1:500~1:2000
ICC/IF 1:50~1:200
IP 1:50
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.

Western blot analysis of LC3B expression in (1) Human brain lysate; (2) RAW 264.7 cell lysate; (3) C6 cell lysate.